Neal B Blatt Selected Research

Bz-423

10/2009	Bz-423 superoxide signals B cell apoptosis via Mcl-1, Bak, and Bax.
11/2008	Bz-423 superoxide signals apoptosis via selective activation of JNK, Bak, and Bax.
10/2003	Structure activity studies of a novel cytotoxic benzodiazepine.
10/2002	Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility.

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Neal B Blatt Research Topics

Disease

4	Acute Kidney Injury (Acute Renal Failure) 01/2016 - 01/2013
3	Sepsis (Septicemia) 01/2021 - 12/2014
2	Glomerulonephritis 12/2021 - 10/2002
2	Bacterial Infections (Bacterial Infection) 01/2021 - 01/2017
2	Inflammation (Inflammations) 01/2017 - 08/2012
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 10/2003 - 10/2002
1	Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II) 12/2021
1	Atypical Hemolytic Uremic Syndrome 01/2021
1	Infections 01/2021
1	Bacteremia 01/2021
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 01/2021
1	Chronic Renal Insufficiency 01/2021
1	Renal Artery Obstruction (Renal Artery Stenosis) 05/2016
1	Aneurysm (Aneurysms) 02/2016
1	Heart Arrest (Cardiac Arrest) 01/2016
1	Multiple Organ Failure (MODS) 05/2015
1	Congenital Heart Defects (Congenital Heart Defect) 10/2013
1	Kidney Diseases (Kidney Disease) 01/2013
1	Acute Lung Injury 08/2012
1	Proteinuria 12/2011
1	Burkitt Lymphoma (Burkitt's Lymphoma) 10/2009
1	Venous Thrombosis (Deep-Vein Thrombosis) 07/2009
1	Psoriasis (Pustulosis Palmaris et Plantaris) 11/2008
1	Rheumatoid Arthritis 10/2003
1	Hyperplasia 10/2002

Drug/Important Bio-Agent (IBA)

4	Bz-423IBA 10/2009 - 10/2002
2	eculizumab FDA Link 12/2021 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 01/2016 - 10/2013
1	Peroxidase (Myeloperoxidase)IBA 12/2021
1	Dichlorodiphenyldichloroethane (DDD)IBA 12/2021
1	Complement System Proteins (Complement)IBA 12/2021
1	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 01/2017
1	EndotoxinsIBA 01/2017
1	Biological ProductsIBA 12/2014
1	CreatinineIBA 01/2013
1	Mitogen-Activated Protein Kinase PhosphatasesIBA 08/2012
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 12/2011
1	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2011
1	BenzodiazepinesIBA 10/2002

Therapy/Procedure

2	Therapeutics 01/2021 - 05/2016
2	Renal Replacement Therapy (Therapies, Renal Replacement) 12/2014 - 01/2013
2	Critical Care (Surgical Intensive Care) 12/2014 - 10/2014
1	Replantation 02/2016
1	Ligation 02/2016
1	Nephrectomy 02/2016
1	Cardiopulmonary Resuscitation (CPR) 01/2016
1	Plasma Exchange 05/2015
1	Extracorporeal Membrane Oxygenation 05/2015
1	Central Venous Catheters 07/2009